Success stories

Abliva AB

abliva-success-story-banner-web.jpg

Established: 2000

Country: Sweden

Region: Skåne

Investors: Hadean Ventures, IP Group, Oslo Pensjonsforsikring AS

Abliva AB was a Lund-based Swedish biotech developing treatments for primary mitochondrial disease (PMD), a group of rare, debilitating disorders.

Its lead candidate, KL1333, is being evaluated in a global Phase 2, potentially registrational clinical trial, in adults with PMD.

Hadean Ventures backed Abliva since 2020, and supported the company strategically through the board of directors – driving the company through regulatory milestones, positive clinical readouts and evolving the management team. The current program delivered encouraging interim data in 2024, reinforcing Abliva’s path toward meaningful therapies for patients.

In December 2024, Pharming announced a recommended cash offer for Abliva with a record-breaking cash premium at +227% - well above the ~75% median premium seen in 2024 life-sciences M&A.

The transaction completed in February 2025, marking a successful exit for Hadean and a strong outcome for European life-science venture.

This case showcases how specialist European VCs can accelerate Nordic science to global impact – combining hands-on company scaling, syndicate leadership, and long-term committed capital.

For patients with PMD and for Europe’s biotech ecosystem, Abliva acts as a blueprint for partnership, impact, and the value venture capital can add in the context of a public company.

kr450mn
total capital raised (since 2020)
+227%
record-breaking cash premium, well above the ~75% median premium seen in 2024 life-sciences M&A
>$1bn
opportunity for EU peak sales

Hadean invested in Abliva because it saw the compelling potential of this mitochondrial disease drug at the same time recognising the value we thought we could bring in terms of strengthening management and refining the strategy. We are gratified that we were able to execute on this vision, bringing in a new CEO, and ultimately the company being sold at a significant premium.

Key achievements

  • Completed Phase 1a/b study of KL1333 in patients with efficacy signals

  • IND approval for Phase II, potentially pivotal FALCON study of KL1333

  • Orphan drug designation for pipeline program NV354

  • Major financing to support initiation of FALCON study

  • Fast track designation by FDA for KL1333

  • Positive interim analysis of FALCON study 

Funding history

  • Total capital raised (since 2020): >SEK 450m in several directed share issues and rights issues

Employment impact

  • Transition of CEO to Ellen Donnely, an experienced US pharma executive

  • Build out of clinical team, delivering sucessful recruitment in a rare disease study 

Find out more

Visit Abliva website