Success stories

Acerta Pharma

B3 Lifesciencesreport Casestudies

Established: 2013

Country: Netherlands

Region: Oss

Investors: BOM, BioGeneration Ventures, Frazier Healthcare Partners (lead)

Acerta Pharma is a leader in the field of covalent binding technology and is applying this knowledge to create a range of highly selective therapies for cancer, most notably leukaemia. The Netherlands-based company’s pioneering treatment Calaquence (acalabrutinib) has been shown to improve the quality of life for adult patients as a viable alternative to aggressive chemotherapy.

Venture capital expertise was instrumental in directing Acerta Pharma towards immuno-oncology. Biogeneration Ventures and BOM Brabant Ventures helped establish the company in 2013 and rapidly progress its treatments into clinical trials1. Following positive results, AstraZeneca acquired a 55% stake in the company at a valuation of $7 billion, including milestone payments. Acerta Pharma’s flagship drug is estimated to achieve potential annual sales in excess of $5 billion globally, with the company now serving as AstraZeneca’s haematology R&D unit2.

IB Acerta Pharma

Pivot Park - Interview Allard Kaptein, founder Acerta Pharma (Video – 03:01)

$60m
raised from VC investors
$4bn
sale of 55% stake to AstraZeneca
200+
jobs created in development of treatment

Key achievements

  • Secured significant investment from AstraZeneca at $7bn valuation, becoming pharma group’s haematology research division

  • US and EU approval for Calaquence, flagship leukaemia treatment for adults

Funding history

  • Raised $60m from VC investors3

  • Sold 55% stake to AstraZeneca for $4bn, including $1.5bn milestone payment4

Employment impact

  • Created over 200 jobs in development of treatments5

Find out more

Visit website

1. https://biogenerationventures.com/en/bgv_case_studies/acerta_pharma
2.
https://www.astrazeneca.com/media-centre/press-releases/2016/astrazeneca-completes-transaction-for-majority-equity-stake-investment-in-acerta-pharma-01022016.html#
3.
https://www.crunchbase.com/organization/acerta-pharma/company_overview/overview_timeline
4.
https://www.astrazeneca.com/media-centre/press-releases/2016/astrazeneca-completes-transaction-for-majority-equity-stake-investment-in-acerta-pharma-01022016.html#
5.
https://www.acerta-pharma.com/about.html#Leadership